Phytochemical and biological studies on piper sarmentosum
Phytochemical and biological studies have been carried out on the leaves of Piper sarmenlOsum. The extracts were subjected to thin layer chromatography, column chromatography and preparative thin layer chromatography in order to isolate and purify pure compounds. Two semi pure compounds with the...
| Main Author: | |
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| Format: | Final Year Project Report / IMRAD |
| Language: | English |
| Published: |
Universiti Malaysia Sarawak (UNIMAS)
2004
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| Subjects: | |
| Online Access: | http://ir.unimas.my/id/eprint/18891/ http://ir.unimas.my/id/eprint/18891/1/Kuan%20full.pdf |
| _version_ | 1848838604362612736 |
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| author | Kuan, Sing Wei. |
| author_facet | Kuan, Sing Wei. |
| author_sort | Kuan, Sing Wei. |
| building | UNIMAS Institutional Repository |
| collection | Online Access |
| description | Phytochemical and biological studies have been carried out on the leaves of Piper
sarmenlOsum. The extracts were subjected to thin layer chromatography, column
chromatography and preparative thin layer chromatography in order to isolate and purify
pure compounds. Two semi pure compounds with the molecular weight of 208 and 270
were isolated. These compounds showed the Rf values of 0.6 and 0.9 in hexane-acetone
(7:3). The mass spectra of MA08A and MA09A showed similarity to standard mass
spectra of isoasarone. Based on the mass spectra and infra red (IR) information,
compound MA09~ most probably be isoasarone. In the toxicity test, most of the
fractions and crude extracts indicated a low toxicity on the larvae of Artemia salina. Only
fractions MA03 and MA09 showed LDso at 10 !lglmL, while for fractions MA04 and
MA08, the LDso value was 55 !lglmL and 40 \.lglmL respectively |
| first_indexed | 2025-11-15T06:58:12Z |
| format | Final Year Project Report / IMRAD |
| id | unimas-18891 |
| institution | Universiti Malaysia Sarawak |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T06:58:12Z |
| publishDate | 2004 |
| publisher | Universiti Malaysia Sarawak (UNIMAS) |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | unimas-188912023-10-31T08:31:44Z http://ir.unimas.my/id/eprint/18891/ Phytochemical and biological studies on piper sarmentosum Kuan, Sing Wei. QK Botany Phytochemical and biological studies have been carried out on the leaves of Piper sarmenlOsum. The extracts were subjected to thin layer chromatography, column chromatography and preparative thin layer chromatography in order to isolate and purify pure compounds. Two semi pure compounds with the molecular weight of 208 and 270 were isolated. These compounds showed the Rf values of 0.6 and 0.9 in hexane-acetone (7:3). The mass spectra of MA08A and MA09A showed similarity to standard mass spectra of isoasarone. Based on the mass spectra and infra red (IR) information, compound MA09~ most probably be isoasarone. In the toxicity test, most of the fractions and crude extracts indicated a low toxicity on the larvae of Artemia salina. Only fractions MA03 and MA09 showed LDso at 10 !lglmL, while for fractions MA04 and MA08, the LDso value was 55 !lglmL and 40 \.lglmL respectively Universiti Malaysia Sarawak (UNIMAS) 2004 Final Year Project Report / IMRAD NonPeerReviewed text en http://ir.unimas.my/id/eprint/18891/1/Kuan%20full.pdf Kuan, Sing Wei. (2004) Phytochemical and biological studies on piper sarmentosum. [Final Year Project Report / IMRAD] (Unpublished) |
| spellingShingle | QK Botany Kuan, Sing Wei. Phytochemical and biological studies on piper sarmentosum |
| title | Phytochemical and biological studies on piper sarmentosum |
| title_full | Phytochemical and biological studies on piper sarmentosum |
| title_fullStr | Phytochemical and biological studies on piper sarmentosum |
| title_full_unstemmed | Phytochemical and biological studies on piper sarmentosum |
| title_short | Phytochemical and biological studies on piper sarmentosum |
| title_sort | phytochemical and biological studies on piper sarmentosum |
| topic | QK Botany |
| url | http://ir.unimas.my/id/eprint/18891/ http://ir.unimas.my/id/eprint/18891/1/Kuan%20full.pdf |