Double Carbonylation Using Glyoxal (HCOCOH): A Practical Copper-Promoted Synthesis of Isatins from Primary and Secondary Anilines
A novel double carbonylation process has been demonstrated with easily available HCOCOH (glyoxal) as the double carbonylation reagent. Simple CuCl2ยท2H2O (copper(II) chloride dihydrate) was used as the oxidant for this transformation. Under optimized reaction conditions, various primary and secondary...
| Main Authors: | , , , , , |
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| Format: | Article |
| Published: |
WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
2017
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| Subjects: | |
| Online Access: | http://ir.unimas.my/id/eprint/17313/ |