A review on lipid-polymer hybrid nanoparticles and preparation with recent update
Ongoing progression in nanotechnology has demonstrated that nanoparticles have indicated promising potential as in delivering the drug. The acceptance of nanoparticles and their applications also reported in clinical advancement to upgrade and improve the pharmacokinetic and pharmacodynamics propert...
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| Format: | Article |
| Language: | English |
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Trans Tech Publications
2020
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| Online Access: | http://umpir.ump.edu.my/id/eprint/30374/ http://umpir.ump.edu.my/id/eprint/30374/1/14.1%20A%20review%20on%20lipid-polymer%20hybrid%20nanoparticles%20and%20preparation%20with%20recent%20update.pdf |
| _version_ | 1848823496775303168 |
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| author | Subashini, Raman Mahmood, Syed Rahman, Azizur |
| author_facet | Subashini, Raman Mahmood, Syed Rahman, Azizur |
| author_sort | Subashini, Raman |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | Ongoing progression in nanotechnology has demonstrated that nanoparticles have indicated promising potential as in delivering the drug. The acceptance of nanoparticles and their applications also reported in clinical advancement to upgrade and improve the pharmacokinetic and pharmacodynamics properties of therapeutic compounds. In this review, we talk about the next-generation core-shell nanostructures like lipid-polymer hybrid nanoparticles (LHNPs) and their application and formulation aspects. Conceptually, derived from both polymeric nanoparticles and liposome, which gave them a name of hybrid nanoparticles. It is basically polymer core enveloped by a lipid layer. The major issue arises with nanoparticles with polymer is related to entrapment efficiency and LHNPs have proved to solve this issue to a vast extent, due to their hybrid components. |
| first_indexed | 2025-11-15T02:58:04Z |
| format | Article |
| id | ump-30374 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T02:58:04Z |
| publishDate | 2020 |
| publisher | Trans Tech Publications |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-303742021-02-05T03:26:23Z http://umpir.ump.edu.my/id/eprint/30374/ A review on lipid-polymer hybrid nanoparticles and preparation with recent update Subashini, Raman Mahmood, Syed Rahman, Azizur T Technology (General) Ongoing progression in nanotechnology has demonstrated that nanoparticles have indicated promising potential as in delivering the drug. The acceptance of nanoparticles and their applications also reported in clinical advancement to upgrade and improve the pharmacokinetic and pharmacodynamics properties of therapeutic compounds. In this review, we talk about the next-generation core-shell nanostructures like lipid-polymer hybrid nanoparticles (LHNPs) and their application and formulation aspects. Conceptually, derived from both polymeric nanoparticles and liposome, which gave them a name of hybrid nanoparticles. It is basically polymer core enveloped by a lipid layer. The major issue arises with nanoparticles with polymer is related to entrapment efficiency and LHNPs have proved to solve this issue to a vast extent, due to their hybrid components. Trans Tech Publications 2020 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/30374/1/14.1%20A%20review%20on%20lipid-polymer%20hybrid%20nanoparticles%20and%20preparation%20with%20recent%20update.pdf Subashini, Raman and Mahmood, Syed and Rahman, Azizur (2020) A review on lipid-polymer hybrid nanoparticles and preparation with recent update. Materials Science Forum, 981. pp. 322-327. ISSN 0255-5476. (Published) https://doi.org/10.4028/www.scientific.net/MSF.981.322 https://doi.org/10.4028/www.scientific.net/MSF.981.322 |
| spellingShingle | T Technology (General) Subashini, Raman Mahmood, Syed Rahman, Azizur A review on lipid-polymer hybrid nanoparticles and preparation with recent update |
| title | A review on lipid-polymer hybrid nanoparticles and preparation with recent update |
| title_full | A review on lipid-polymer hybrid nanoparticles and preparation with recent update |
| title_fullStr | A review on lipid-polymer hybrid nanoparticles and preparation with recent update |
| title_full_unstemmed | A review on lipid-polymer hybrid nanoparticles and preparation with recent update |
| title_short | A review on lipid-polymer hybrid nanoparticles and preparation with recent update |
| title_sort | review on lipid-polymer hybrid nanoparticles and preparation with recent update |
| topic | T Technology (General) |
| url | http://umpir.ump.edu.my/id/eprint/30374/ http://umpir.ump.edu.my/id/eprint/30374/ http://umpir.ump.edu.my/id/eprint/30374/ http://umpir.ump.edu.my/id/eprint/30374/1/14.1%20A%20review%20on%20lipid-polymer%20hybrid%20nanoparticles%20and%20preparation%20with%20recent%20update.pdf |