High-Resolution Laser-Assisted Magnetic Nanoparticle Imaging Using a High-TC SQUID Magnetometer

A new type of magnetic nanoparticle imaging (MPI) system has been proposed and developed. The spatial resolution of MPI systems is generally determined and limited by the size of the magnetic sensors used and the magnetic properties of the nanoparticles detected. Here, high-resolution imaging of mag...

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Main Authors: Kiwa, Toshihiko, Koji, Morita, Matsunaga, Yasuaki, Mohd Mawardi, Saari, Sakai, Kenji, Tsukada, Keiji
Format: Article
Language:English
Published: IEEE 2017
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/14288/
http://umpir.ump.edu.my/id/eprint/14288/2/High-Resolution%20Laser-Assisted%20Magnetic%20Nanoparticle%20Imaging%20Using%20a%20High-TC%20SQUID%20Magnetometer%201.pdf
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author Kiwa, Toshihiko
Koji, Morita
Matsunaga, Yasuaki
Mohd Mawardi, Saari
Sakai, Kenji
Tsukada, Keiji
author_facet Kiwa, Toshihiko
Koji, Morita
Matsunaga, Yasuaki
Mohd Mawardi, Saari
Sakai, Kenji
Tsukada, Keiji
author_sort Kiwa, Toshihiko
building UMP Institutional Repository
collection Online Access
description A new type of magnetic nanoparticle imaging (MPI) system has been proposed and developed. The spatial resolution of MPI systems is generally determined and limited by the size of the magnetic sensors used and the magnetic properties of the nanoparticles detected. Here, high-resolution imaging of magnetic particles was realized by combining the MPI system with a high-TC SQUID magnetometer and laser scanning system. The spatial resolution of this system was not determined by the properties of the magnetic nanoparticles but was determined by the laser spot size focused on samples. Thus, the higher spatial resolution imparted by conventional MPI systems could be expected. As a demonstration of the imaging system, two cylindrical containers filled with magnetic particles solutions were fabricated and measured. Although the containers were spaced only 2 mm apart, they could be clearly distinguished by the obtained signals. A knife-edge analysis was also applied to the obtained signals, and the spatial resolution of our system was estimated to be approximately 0.9 mm.
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institution Universiti Malaysia Pahang
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language English
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publishDate 2017
publisher IEEE
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spelling ump-142882018-05-18T06:13:33Z http://umpir.ump.edu.my/id/eprint/14288/ High-Resolution Laser-Assisted Magnetic Nanoparticle Imaging Using a High-TC SQUID Magnetometer Kiwa, Toshihiko Koji, Morita Matsunaga, Yasuaki Mohd Mawardi, Saari Sakai, Kenji Tsukada, Keiji TK Electrical engineering. Electronics Nuclear engineering A new type of magnetic nanoparticle imaging (MPI) system has been proposed and developed. The spatial resolution of MPI systems is generally determined and limited by the size of the magnetic sensors used and the magnetic properties of the nanoparticles detected. Here, high-resolution imaging of magnetic particles was realized by combining the MPI system with a high-TC SQUID magnetometer and laser scanning system. The spatial resolution of this system was not determined by the properties of the magnetic nanoparticles but was determined by the laser spot size focused on samples. Thus, the higher spatial resolution imparted by conventional MPI systems could be expected. As a demonstration of the imaging system, two cylindrical containers filled with magnetic particles solutions were fabricated and measured. Although the containers were spaced only 2 mm apart, they could be clearly distinguished by the obtained signals. A knife-edge analysis was also applied to the obtained signals, and the spatial resolution of our system was estimated to be approximately 0.9 mm. IEEE 2017 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/14288/2/High-Resolution%20Laser-Assisted%20Magnetic%20Nanoparticle%20Imaging%20Using%20a%20High-TC%20SQUID%20Magnetometer%201.pdf Kiwa, Toshihiko and Koji, Morita and Matsunaga, Yasuaki and Mohd Mawardi, Saari and Sakai, Kenji and Tsukada, Keiji (2017) High-Resolution Laser-Assisted Magnetic Nanoparticle Imaging Using a High-TC SQUID Magnetometer. IEEE Transactions on Applied Superconductivity, 27 (4). pp. 1-4. ISSN 1051-8223 (Print); 1558-2515 (Online). (Published) http://ieeexplore.ieee.org/stamp/stamp.jsp?arnumber=7828087 DOI: 10.1109/TASC.2017.2656118
spellingShingle TK Electrical engineering. Electronics Nuclear engineering
Kiwa, Toshihiko
Koji, Morita
Matsunaga, Yasuaki
Mohd Mawardi, Saari
Sakai, Kenji
Tsukada, Keiji
High-Resolution Laser-Assisted Magnetic Nanoparticle Imaging Using a High-TC SQUID Magnetometer
title High-Resolution Laser-Assisted Magnetic Nanoparticle Imaging Using a High-TC SQUID Magnetometer
title_full High-Resolution Laser-Assisted Magnetic Nanoparticle Imaging Using a High-TC SQUID Magnetometer
title_fullStr High-Resolution Laser-Assisted Magnetic Nanoparticle Imaging Using a High-TC SQUID Magnetometer
title_full_unstemmed High-Resolution Laser-Assisted Magnetic Nanoparticle Imaging Using a High-TC SQUID Magnetometer
title_short High-Resolution Laser-Assisted Magnetic Nanoparticle Imaging Using a High-TC SQUID Magnetometer
title_sort high-resolution laser-assisted magnetic nanoparticle imaging using a high-tc squid magnetometer
topic TK Electrical engineering. Electronics Nuclear engineering
url http://umpir.ump.edu.my/id/eprint/14288/
http://umpir.ump.edu.my/id/eprint/14288/
http://umpir.ump.edu.my/id/eprint/14288/
http://umpir.ump.edu.my/id/eprint/14288/2/High-Resolution%20Laser-Assisted%20Magnetic%20Nanoparticle%20Imaging%20Using%20a%20High-TC%20SQUID%20Magnetometer%201.pdf