Antimicrobial and antibiofilm activities of the methanol extracts of rosa damascena against s. aureus / Indah Mohd Amin … [et al.]
The aims of this study are to investigate antibacterial and antibiofilm activity of Rosa damascena (R.damascena) flower extract against Staphylococcus aureus (S. aureus). Method: The antibacterial activity was assessed with minimum inhibitory concentration (MIC) and minimum bactericidal concentratio...
| Main Authors: | , , , , |
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| Format: | Conference or Workshop Item |
| Language: | English |
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2019
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| Online Access: | https://ir.uitm.edu.my/id/eprint/30163/ |
| _version_ | 1848807425703936000 |
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| author | Mohd Amin, Indah Mohamad Zain, Nurhayati Ahmad, Vivi Noryati Mat Daud, Dzulfakhrul Najwan Abdullah Sani, Nabilah |
| author_facet | Mohd Amin, Indah Mohamad Zain, Nurhayati Ahmad, Vivi Noryati Mat Daud, Dzulfakhrul Najwan Abdullah Sani, Nabilah |
| author_sort | Mohd Amin, Indah |
| building | UiTM Institutional Repository |
| collection | Online Access |
| description | The aims of this study are to investigate antibacterial and antibiofilm activity of Rosa damascena (R.damascena) flower extract against Staphylococcus aureus (S. aureus). Method: The antibacterial activity was assessed with minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). The potential of R.damascena flower extract as an antibiofilm agent was evaluated using biofilm inhibition assay and biofilm eradication assay. Chlorhexidine (CHX) 0.12% was used as a positive control. The experiment was performed in triplicate and repeated four times independently. All the data obtained were analysed using SPSS version 23. A Kruskal-Wallis test followed by post-hoc Mann-Whitney U test and level of significance was set at P < 0.05. Results: From this study, R.damascena extract shows antibacterial activity with MIC 50 mg/ml and MBC 100 mg/ml. Treatment with 0.5 MIC of extract inhibited 43.2% of biofilm formation. The biofilm eradication assay shows that 60.9% (p<0.001) of biofilm was eradicated by the extract upon 5 minutes treatment and 50.65% by 0.12% CHX. Conclusion: The result of this in-vitro study suggests a possible utilisation of R.damascena flower extract in treating S. aureus biofilm-associated infection in the oral environment. |
| first_indexed | 2025-11-14T22:42:37Z |
| format | Conference or Workshop Item |
| id | uitm-30163 |
| institution | Universiti Teknologi MARA |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T22:42:37Z |
| publishDate | 2019 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | uitm-301632020-04-23T02:52:12Z https://ir.uitm.edu.my/id/eprint/30163/ Antimicrobial and antibiofilm activities of the methanol extracts of rosa damascena against s. aureus / Indah Mohd Amin … [et al.] Mohd Amin, Indah Mohamad Zain, Nurhayati Ahmad, Vivi Noryati Mat Daud, Dzulfakhrul Najwan Abdullah Sani, Nabilah Individual drugs and other agents Materia medica The aims of this study are to investigate antibacterial and antibiofilm activity of Rosa damascena (R.damascena) flower extract against Staphylococcus aureus (S. aureus). Method: The antibacterial activity was assessed with minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). The potential of R.damascena flower extract as an antibiofilm agent was evaluated using biofilm inhibition assay and biofilm eradication assay. Chlorhexidine (CHX) 0.12% was used as a positive control. The experiment was performed in triplicate and repeated four times independently. All the data obtained were analysed using SPSS version 23. A Kruskal-Wallis test followed by post-hoc Mann-Whitney U test and level of significance was set at P < 0.05. Results: From this study, R.damascena extract shows antibacterial activity with MIC 50 mg/ml and MBC 100 mg/ml. Treatment with 0.5 MIC of extract inhibited 43.2% of biofilm formation. The biofilm eradication assay shows that 60.9% (p<0.001) of biofilm was eradicated by the extract upon 5 minutes treatment and 50.65% by 0.12% CHX. Conclusion: The result of this in-vitro study suggests a possible utilisation of R.damascena flower extract in treating S. aureus biofilm-associated infection in the oral environment. 2019 Conference or Workshop Item PeerReviewed text en https://ir.uitm.edu.my/id/eprint/30163/1/K_INDAH%20MOHD%20AMIN%20DSSS%20B%2019.pdf Mohd Amin, Indah and Mohamad Zain, Nurhayati and Ahmad, Vivi Noryati and Mat Daud, Dzulfakhrul Najwan and Abdullah Sani, Nabilah (2019) Antimicrobial and antibiofilm activities of the methanol extracts of rosa damascena against s. aureus / Indah Mohd Amin … [et al.]. (2019) In: Proceedings of 9th Dental Student’s Scientific Symposium,Malaysia (Malaysia, 2019), 9th – 10th April 2019, Faculty Dentistry, Universiti Teknologi MARA. https://dentistry.uitm.edu.my/v2/images/images/DSS/proceeding/vol1/pdf/12.pdf? |
| spellingShingle | Individual drugs and other agents Materia medica Mohd Amin, Indah Mohamad Zain, Nurhayati Ahmad, Vivi Noryati Mat Daud, Dzulfakhrul Najwan Abdullah Sani, Nabilah Antimicrobial and antibiofilm activities of the methanol extracts of rosa damascena against s. aureus / Indah Mohd Amin … [et al.] |
| title | Antimicrobial and antibiofilm activities of the methanol extracts of rosa damascena against s. aureus / Indah Mohd Amin … [et al.] |
| title_full | Antimicrobial and antibiofilm activities of the methanol extracts of rosa damascena against s. aureus / Indah Mohd Amin … [et al.] |
| title_fullStr | Antimicrobial and antibiofilm activities of the methanol extracts of rosa damascena against s. aureus / Indah Mohd Amin … [et al.] |
| title_full_unstemmed | Antimicrobial and antibiofilm activities of the methanol extracts of rosa damascena against s. aureus / Indah Mohd Amin … [et al.] |
| title_short | Antimicrobial and antibiofilm activities of the methanol extracts of rosa damascena against s. aureus / Indah Mohd Amin … [et al.] |
| title_sort | antimicrobial and antibiofilm activities of the methanol extracts of rosa damascena against s. aureus / indah mohd amin … [et al.] |
| topic | Individual drugs and other agents Materia medica |
| url | https://ir.uitm.edu.my/id/eprint/30163/ https://ir.uitm.edu.my/id/eprint/30163/ |