The invisible evil twin of an adrenal adenoma / Aimi Fadilah M … [et al.]
Primary aldosteronism (PA) causes a persistently elevated blood pressure (BP) due to excessive release of the hormone aldosterone from the adrenal glands. Classically, it is called Conn’s syndrome and is described as the triad of hypertension and hypokalemia with the presence of unilateral adrenal a...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Universiti Teknologi MARA Cawangan Selangor
2019
|
| Subjects: | |
| Online Access: | https://ir.uitm.edu.my/id/eprint/30048/ |
| _version_ | 1848807398903382016 |
|---|---|
| author | Mohamad, Aimi Fadilah Mohamed Shah, Fatimah Zaherah Zainordin, Nur Aisyah Eddy Warman, ur 'Aini Ab Mumin, Nazimah Omar, Effat Abdul Ghani, Rohana |
| author_facet | Mohamad, Aimi Fadilah Mohamed Shah, Fatimah Zaherah Zainordin, Nur Aisyah Eddy Warman, ur 'Aini Ab Mumin, Nazimah Omar, Effat Abdul Ghani, Rohana |
| author_sort | Mohamad, Aimi Fadilah |
| building | UiTM Institutional Repository |
| collection | Online Access |
| description | Primary aldosteronism (PA) causes a persistently elevated blood pressure (BP) due to excessive release of the hormone aldosterone from the adrenal glands. Classically, it is called Conn’s syndrome and is described as the triad of hypertension and hypokalemia with the presence of unilateral adrenal adenoma. It can be cured with surgical resection of the aldosterone-secreting adenoma leading to resolution of hypertension, hypokalemia and increased cardiovascular risk associated with hyperaldosteronism. We present a case of a man with previous ischemic heart disease (IHD) who presented with resistant hypertension. Investigations for secondary causes of hypertension revealed an elevated aldosterone level and saline suppression test confirmed the diagnosis of PA. Radiological examination revealed a left adrenal adenoma and a normal right adrenal gland. However, adrenal venous sampling showed lateralization of aldosterone secretion towards the right. He subsequently underwent a laparoscopic right adrenalectomy which improved his BP control promptly. This case highlights the importance of recognizing the need to investigate for secondary causes of hypertension. It also underscores the importance of dynamic tests, which may not be easily accessible to most clinicians but should pursue, to allow a definitive diagnosis and effective treatment. |
| first_indexed | 2025-11-14T22:42:12Z |
| format | Article |
| id | uitm-30048 |
| institution | Universiti Teknologi MARA |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T22:42:12Z |
| publishDate | 2019 |
| publisher | Universiti Teknologi MARA Cawangan Selangor |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | uitm-300482020-04-21T13:27:49Z https://ir.uitm.edu.my/id/eprint/30048/ The invisible evil twin of an adrenal adenoma / Aimi Fadilah M … [et al.] jchs Mohamad, Aimi Fadilah Mohamed Shah, Fatimah Zaherah Zainordin, Nur Aisyah Eddy Warman, ur 'Aini Ab Mumin, Nazimah Omar, Effat Abdul Ghani, Rohana QP Physiology Cerebral cortex Auditory cortex. Sensorimotor cortex Primary aldosteronism (PA) causes a persistently elevated blood pressure (BP) due to excessive release of the hormone aldosterone from the adrenal glands. Classically, it is called Conn’s syndrome and is described as the triad of hypertension and hypokalemia with the presence of unilateral adrenal adenoma. It can be cured with surgical resection of the aldosterone-secreting adenoma leading to resolution of hypertension, hypokalemia and increased cardiovascular risk associated with hyperaldosteronism. We present a case of a man with previous ischemic heart disease (IHD) who presented with resistant hypertension. Investigations for secondary causes of hypertension revealed an elevated aldosterone level and saline suppression test confirmed the diagnosis of PA. Radiological examination revealed a left adrenal adenoma and a normal right adrenal gland. However, adrenal venous sampling showed lateralization of aldosterone secretion towards the right. He subsequently underwent a laparoscopic right adrenalectomy which improved his BP control promptly. This case highlights the importance of recognizing the need to investigate for secondary causes of hypertension. It also underscores the importance of dynamic tests, which may not be easily accessible to most clinicians but should pursue, to allow a definitive diagnosis and effective treatment. Universiti Teknologi MARA Cawangan Selangor 2019-06 Article PeerReviewed text en https://ir.uitm.edu.my/id/eprint/30048/1/AJ_AIMI%20FADILAH%20MOHAMAD%20JCHS%20B%2019.pdf Mohamad, Aimi Fadilah and Mohamed Shah, Fatimah Zaherah and Zainordin, Nur Aisyah and Eddy Warman, ur 'Aini and Ab Mumin, Nazimah and Omar, Effat and Abdul Ghani, Rohana (2019) The invisible evil twin of an adrenal adenoma / Aimi Fadilah M … [et al.]. (2019) Journal of Clinical and Health Sciences <https://ir.uitm.edu.my/view/publication/Journal_of_Clinical_and_Health_Sciences.html>, 4 (1). pp. 1-6. ISSN 0127-984X https://jchs-medicine.uitm.edu.my/index.php |
| spellingShingle | QP Physiology Cerebral cortex Auditory cortex. Sensorimotor cortex Mohamad, Aimi Fadilah Mohamed Shah, Fatimah Zaherah Zainordin, Nur Aisyah Eddy Warman, ur 'Aini Ab Mumin, Nazimah Omar, Effat Abdul Ghani, Rohana The invisible evil twin of an adrenal adenoma / Aimi Fadilah M … [et al.] |
| title | The invisible evil twin of an adrenal adenoma / Aimi Fadilah M … [et al.] |
| title_full | The invisible evil twin of an adrenal adenoma / Aimi Fadilah M … [et al.] |
| title_fullStr | The invisible evil twin of an adrenal adenoma / Aimi Fadilah M … [et al.] |
| title_full_unstemmed | The invisible evil twin of an adrenal adenoma / Aimi Fadilah M … [et al.] |
| title_short | The invisible evil twin of an adrenal adenoma / Aimi Fadilah M … [et al.] |
| title_sort | invisible evil twin of an adrenal adenoma / aimi fadilah m … [et al.] |
| topic | QP Physiology Cerebral cortex Auditory cortex. Sensorimotor cortex |
| url | https://ir.uitm.edu.my/id/eprint/30048/ https://ir.uitm.edu.my/id/eprint/30048/ |