A multicomponent reaction of 2-aminoimidazoles: microwave-assisted synthesis of novel 5-aza-7- deaza-adenines†‡
An efficient and highly selective multicomponent synthesis of 4-aminoimidazo[1,2-a][1,3,5]triazines, which are 5-aza-7-deaza-isosteres of adenine, was developed. The reaction of 2-aminoimidazoles, triethyl orthoformate and cyanamide under microwave irradiation proceeded regioselectively to provide...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Royal Society of Chemistry
2017
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| Subjects: | |
| Online Access: | http://eprints.sunway.edu.my/712/ http://eprints.sunway.edu.my/712/1/Tiekink%20A%20multicomponent%20RSC%20Adv%202017%20.pdf |