3,4-Diaminopyrazolo[3,4-d]pyrimidines: a new three-component microwave-assisted synthesis and anti-leukemic properties

A convenient method for the synthesis of N3,N4-disubstituted 3,4-diaminopyrazolo[3,4-d]pyrimidines was developed using a three-component reaction of 3,5-diaminopyrazole-4-carbonitriles with primary amines and orthoesters. The preparation of 114 examples demonstrated the good scope of the reaction, w...

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Bibliographic Details
Main Authors: Ng, Jia Hui, Lim, Felicia Phei Lin, Tiekink, Edward R. T. *, Dolzhenko, Anton V
Format: Article
Language:English
Published: Royal Society of Chemistry 2023
Subjects:
Online Access:http://eprints.sunway.edu.my/2178/
http://eprints.sunway.edu.my/2178/1/org%20biomol%20chem%202023%2021%203432.pdf