Development of live attenuated Enterovirus 71 vaccine strains that confer protection against lethal challenge in mice

Besides causing mild hand, foot and mouth infections, Enterovirus A71 (EV-A71) is associated with neurological complications and fatality. With concerns about rising EV-A71 virulence, there is an urgency for more efective vaccines. The live attenuated vaccine (LAV) is a more valuable vaccine as it c...

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Bibliographic Details
Main Authors: Yee, Isabel Pin Tsin *, Tan, Soon Hao, Ong, Kien Chai, Tan, Kuan Onn *, Wong, Kum Thong, Sharifah Syed Hassan, Poh, Chit Laa *
Format: Article
Language:English
Published: Nature Research 2019
Subjects:
Online Access:http://eprints.sunway.edu.my/1099/
http://eprints.sunway.edu.my/1099/1/Poh_Development%20of%20live%20attenuated%20Enterovirus%2071.pdf