The Rare Primary Low Grade Papillary Adenocarcinoma of Nasopharynx: A Diagnostic Challenge and Management
Low Grade Papillary Nasopharyngeal Adenocarcinoma (LGPAC) is a very rare tumour of mucosal origin compared to a higher incidence of well differentiated keratinized/non-keratinized nasopharyngeal carcinoma. It is an epithelial tumour with glandular differentiation. Its papillary figure seen histologi...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Penerbit UKM
2015
|
| Online Access: | http://journalarticle.ukm.my/9280/ http://journalarticle.ukm.my/9280/1/7.%2520Noor%2520Dina%2520H%2520et%2520al..pdf |
| _version_ | 1848812034642149376 |
|---|---|
| author | Noor Dina H, Gendeh BH, |
| author_facet | Noor Dina H, Gendeh BH, |
| author_sort | Noor Dina H, |
| building | UKM Institutional Repository |
| collection | Online Access |
| description | Low Grade Papillary Nasopharyngeal Adenocarcinoma (LGPAC) is a very rare tumour of mucosal origin compared to a higher incidence of well differentiated keratinized/non-keratinized nasopharyngeal carcinoma. It is an epithelial tumour with glandular differentiation. Its papillary figure seen histologically, is also seen in metastatic papillary thyroid carcinoma. This has caused a significant challenge to the Pathologist to differentiate primary papillary nasopharyngeal adenocarcinoma and metastatic tumour. Thyroid Transcription Factor-1 (TTF-1) is also expressed in subsets of papillary nasopharyngeal adenocarcinoma, which is valuable as a diagnostic tool. LGPAC is a benign-like malignant neoplasm. An early diagnosis with a complete tumour removal via conventional excision or endoscopic approach has offered a good prognosis with low risk of recurrence. |
| first_indexed | 2025-11-14T23:55:53Z |
| format | Article |
| id | oai:generic.eprints.org:9280 |
| institution | Universiti Kebangasaan Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T23:55:53Z |
| publishDate | 2015 |
| publisher | Penerbit UKM |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | oai:generic.eprints.org:92802016-12-14T06:49:27Z http://journalarticle.ukm.my/9280/ The Rare Primary Low Grade Papillary Adenocarcinoma of Nasopharynx: A Diagnostic Challenge and Management Noor Dina H, Gendeh BH, Low Grade Papillary Nasopharyngeal Adenocarcinoma (LGPAC) is a very rare tumour of mucosal origin compared to a higher incidence of well differentiated keratinized/non-keratinized nasopharyngeal carcinoma. It is an epithelial tumour with glandular differentiation. Its papillary figure seen histologically, is also seen in metastatic papillary thyroid carcinoma. This has caused a significant challenge to the Pathologist to differentiate primary papillary nasopharyngeal adenocarcinoma and metastatic tumour. Thyroid Transcription Factor-1 (TTF-1) is also expressed in subsets of papillary nasopharyngeal adenocarcinoma, which is valuable as a diagnostic tool. LGPAC is a benign-like malignant neoplasm. An early diagnosis with a complete tumour removal via conventional excision or endoscopic approach has offered a good prognosis with low risk of recurrence. Penerbit UKM 2015-12-01 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/9280/1/7.%2520Noor%2520Dina%2520H%2520et%2520al..pdf Noor Dina H, and Gendeh BH, (2015) The Rare Primary Low Grade Papillary Adenocarcinoma of Nasopharynx: A Diagnostic Challenge and Management. Medicine & Health, 10 (2). pp. 137-140. ISSN 1823-2140 http://www.medicineandhealthukm.com |
| spellingShingle | Noor Dina H, Gendeh BH, The Rare Primary Low Grade Papillary Adenocarcinoma of Nasopharynx: A Diagnostic Challenge and Management |
| title | The Rare Primary Low Grade Papillary Adenocarcinoma of Nasopharynx: A Diagnostic Challenge and Management |
| title_full | The Rare Primary Low Grade Papillary Adenocarcinoma of Nasopharynx: A Diagnostic Challenge and Management |
| title_fullStr | The Rare Primary Low Grade Papillary Adenocarcinoma of Nasopharynx: A Diagnostic Challenge and Management |
| title_full_unstemmed | The Rare Primary Low Grade Papillary Adenocarcinoma of Nasopharynx: A Diagnostic Challenge and Management |
| title_short | The Rare Primary Low Grade Papillary Adenocarcinoma of Nasopharynx: A Diagnostic Challenge and Management |
| title_sort | rare primary low grade papillary adenocarcinoma of nasopharynx: a diagnostic challenge and management |
| url | http://journalarticle.ukm.my/9280/ http://journalarticle.ukm.my/9280/ http://journalarticle.ukm.my/9280/1/7.%2520Noor%2520Dina%2520H%2520et%2520al..pdf |