Inflamatory Pseudotumor of the Bladder: A Histopathological Diagnostic Challenge from Its Malignant Variant.

Inflammatory Pseudotumor (IP) of bladder is one of a variety of lesions which may arise from spindle cell lesions in the bladder. It is benign in nature compared to the other end of the spectrum of spindle cell lesions, such as sarcoma, sarcomatoid carcinoma and leiomyosarcoma. The diagnosis of IP a...

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Main Authors: Muhammad Akbar, S, Praveen, HCK, Christopher, EH, Goh, Swaminathan, Zulkifli MZ
Format: Article
Language:English
Published: Department of Surgery, UKM Medical Centre 2012
Online Access:http://journalarticle.ukm.my/5239/
http://journalarticle.ukm.my/5239/1/13-MS1046%2846-49%29.pdf
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author Muhammad Akbar,
S, Praveen
HCK, Christopher
EH, Goh
Swaminathan,
Zulkifli MZ,
author_facet Muhammad Akbar,
S, Praveen
HCK, Christopher
EH, Goh
Swaminathan,
Zulkifli MZ,
author_sort Muhammad Akbar,
building UKM Institutional Repository
collection Online Access
description Inflammatory Pseudotumor (IP) of bladder is one of a variety of lesions which may arise from spindle cell lesions in the bladder. It is benign in nature compared to the other end of the spectrum of spindle cell lesions, such as sarcoma, sarcomatoid carcinoma and leiomyosarcoma. The diagnosis of IP and its differentiation from a malignant pathology is a diagnostic dilemma for Urologist and Pathologist as both entities share certain similar morphological and histo-pathological appearance as well as immuno-histo chemistry staining. It is however crucial to avoid misdiagnosis as the treatment option varies significantly between a radical or partial cystectomy with future surveillance cystoscopes. Hereby, we highlight a case of a benign variant of spindle cell tumour of bladder which needed second pathology review for confirmation and thus avoiding a radical cystectomy. We also review the literature on its presentation and emphasis characteristics differentiating a benign from a malignant pathology.
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spelling oai:generic.eprints.org:52392016-12-14T06:37:54Z http://journalarticle.ukm.my/5239/ Inflamatory Pseudotumor of the Bladder: A Histopathological Diagnostic Challenge from Its Malignant Variant. Muhammad Akbar, S, Praveen HCK, Christopher EH, Goh Swaminathan, Zulkifli MZ, Inflammatory Pseudotumor (IP) of bladder is one of a variety of lesions which may arise from spindle cell lesions in the bladder. It is benign in nature compared to the other end of the spectrum of spindle cell lesions, such as sarcoma, sarcomatoid carcinoma and leiomyosarcoma. The diagnosis of IP and its differentiation from a malignant pathology is a diagnostic dilemma for Urologist and Pathologist as both entities share certain similar morphological and histo-pathological appearance as well as immuno-histo chemistry staining. It is however crucial to avoid misdiagnosis as the treatment option varies significantly between a radical or partial cystectomy with future surveillance cystoscopes. Hereby, we highlight a case of a benign variant of spindle cell tumour of bladder which needed second pathology review for confirmation and thus avoiding a radical cystectomy. We also review the literature on its presentation and emphasis characteristics differentiating a benign from a malignant pathology. Department of Surgery, UKM Medical Centre 2012-02-25 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/5239/1/13-MS1046%2846-49%29.pdf Muhammad Akbar, and S, Praveen and HCK, Christopher and EH, Goh and Swaminathan, and Zulkifli MZ, (2012) Inflamatory Pseudotumor of the Bladder: A Histopathological Diagnostic Challenge from Its Malignant Variant. Journal of Surgical Academia, 2 (1). pp. 46-49. ISSN 2231-7481 http://jsurgacad.com/
spellingShingle Muhammad Akbar,
S, Praveen
HCK, Christopher
EH, Goh
Swaminathan,
Zulkifli MZ,
Inflamatory Pseudotumor of the Bladder: A Histopathological Diagnostic Challenge from Its Malignant Variant.
title Inflamatory Pseudotumor of the Bladder: A Histopathological Diagnostic Challenge from Its Malignant Variant.
title_full Inflamatory Pseudotumor of the Bladder: A Histopathological Diagnostic Challenge from Its Malignant Variant.
title_fullStr Inflamatory Pseudotumor of the Bladder: A Histopathological Diagnostic Challenge from Its Malignant Variant.
title_full_unstemmed Inflamatory Pseudotumor of the Bladder: A Histopathological Diagnostic Challenge from Its Malignant Variant.
title_short Inflamatory Pseudotumor of the Bladder: A Histopathological Diagnostic Challenge from Its Malignant Variant.
title_sort inflamatory pseudotumor of the bladder: a histopathological diagnostic challenge from its malignant variant.
url http://journalarticle.ukm.my/5239/
http://journalarticle.ukm.my/5239/
http://journalarticle.ukm.my/5239/1/13-MS1046%2846-49%29.pdf