Benzalhydantoin derivative-based inhibitors of eight receptor tyrosine kinases: synthesis, in-vitro, and in-silico study

Some hydantoin derivatives have been explored for their potential as anticancer agents by inhibiting receptor tyrosine kinases (RTKs). Benzalhydantoin derivatives were obtained from a two-step reaction: condensation and alkylation reaction. The benzalhydantoin activities were obtained from the enzym...

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Bibliographic Details
Main Authors: Muhammad Naufal, Hidayat, Ika Wiani, Hermawati, Elvira, Syah, Yana Maolana, Al-Anshori, Jamaludin
Format: Article
Language:English
Published: Penerbit Universiti Kebangsaan Malaysia 2025
Online Access:http://journalarticle.ukm.my/25066/
http://journalarticle.ukm.my/25066/1/SSB%2016.pdf