Optimization of effervescent tablet-assisted dispersive liquid-liquid microextraction with central composite design for preconcentration of stimulant drug

The extraction efficiency of stimulant drug, namely caffeine, was investigated using a 23 central composite design. The values of optimum extraction condition were set at 468 µL of 1-dodecanol, 1 piece of effervescent tablet, and 22 °C of extraction temperature. An enrichment factor was calcul...

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Bibliographic Details
Main Authors: Nurliyana Tazulazhar, Loh, Saw Hong, Marinah Mohd Ariffin, Wan Mohd Afiq Wan Mohd Khalik
Format: Article
Language:English
Published: Penerbit Universiti Kebangsaan Malaysia 2021
Online Access:http://journalarticle.ukm.my/16397/
http://journalarticle.ukm.my/16397/1/12.pdf