Defining the prevalence and predictors of restrictive and obstructive airway pattern in a non-selected Malaysian population

The incidence of chronic obstructive pulmonary disease (COPD) in Malaysia appear to be increasing. To date, there are no local studies describing restrictive and obstructive airflow limitation patterns using spirometry. We conducted a cross�sectional study to determine the prevalence and predict...

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Main Authors: Faisal AH, Andrea Ban Yu-Lin, Nina M, Ahmad Izuanuddin I, Tidi H
Format: Article
Language:English
Published: Pusat Perubatan Universiti Kebangsaan Malaysia 2020
Online Access:http://journalarticle.ukm.my/16276/
http://journalarticle.ukm.my/16276/1/14_ms0422_pdf_21957.pdf
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author Faisal AH,
Andrea Ban Yu-Lin,
Nina M,
Ahmad Izuanuddin I,
Tidi H,
author_facet Faisal AH,
Andrea Ban Yu-Lin,
Nina M,
Ahmad Izuanuddin I,
Tidi H,
author_sort Faisal AH,
building UKM Institutional Repository
collection Online Access
description The incidence of chronic obstructive pulmonary disease (COPD) in Malaysia appear to be increasing. To date, there are no local studies describing restrictive and obstructive airflow limitation patterns using spirometry. We conducted a cross�sectional study to determine the prevalence and predictors of airflow limitation symptoms by screening for COPD symptoms with the COPD Population Screener (COPD-PS) questionnaire and determined the airflow limitation using the new hand-held device, AirSmart®. We recruited 265 subjects. Eleven percent had restrictive pattern and 16% had obstructive pattern. Twenty percent of subjects had COPD-PS score of more than five. In the obstructive pattern group, 74% were active or ex-smokers (p=0.03, p<0.01), whilst those with restrictive pattern were more likely to be heavier with a body mass index (BMI) of more than 23 (OR 2.52, 95% CI: 1.02-5.62) (p<0.01). There was a negative correlation between forced vital capacity and BMI (r=-0.5813, p<0.001). We found a high prevalence restrictive pattern of airflow limitation using the new AirSmart® Spirometer. There appeared to be a large proportion of undiagnosed obstructive airway diseases and higher BMI could be the causes of limitation of airflow in our subjects.
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spelling oai:generic.eprints.org:162762021-03-16T01:59:18Z http://journalarticle.ukm.my/16276/ Defining the prevalence and predictors of restrictive and obstructive airway pattern in a non-selected Malaysian population Faisal AH, Andrea Ban Yu-Lin, Nina M, Ahmad Izuanuddin I, Tidi H, The incidence of chronic obstructive pulmonary disease (COPD) in Malaysia appear to be increasing. To date, there are no local studies describing restrictive and obstructive airflow limitation patterns using spirometry. We conducted a cross�sectional study to determine the prevalence and predictors of airflow limitation symptoms by screening for COPD symptoms with the COPD Population Screener (COPD-PS) questionnaire and determined the airflow limitation using the new hand-held device, AirSmart®. We recruited 265 subjects. Eleven percent had restrictive pattern and 16% had obstructive pattern. Twenty percent of subjects had COPD-PS score of more than five. In the obstructive pattern group, 74% were active or ex-smokers (p=0.03, p<0.01), whilst those with restrictive pattern were more likely to be heavier with a body mass index (BMI) of more than 23 (OR 2.52, 95% CI: 1.02-5.62) (p<0.01). There was a negative correlation between forced vital capacity and BMI (r=-0.5813, p<0.001). We found a high prevalence restrictive pattern of airflow limitation using the new AirSmart® Spirometer. There appeared to be a large proportion of undiagnosed obstructive airway diseases and higher BMI could be the causes of limitation of airflow in our subjects. Pusat Perubatan Universiti Kebangsaan Malaysia 2020-12 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/16276/1/14_ms0422_pdf_21957.pdf Faisal AH, and Andrea Ban Yu-Lin, and Nina M, and Ahmad Izuanuddin I, and Tidi H, (2020) Defining the prevalence and predictors of restrictive and obstructive airway pattern in a non-selected Malaysian population. Medicine & Health, 15 (2). pp. 140-152. ISSN 2289-5728 https://www.medicineandhealthukm.com/toc/15/2
spellingShingle Faisal AH,
Andrea Ban Yu-Lin,
Nina M,
Ahmad Izuanuddin I,
Tidi H,
Defining the prevalence and predictors of restrictive and obstructive airway pattern in a non-selected Malaysian population
title Defining the prevalence and predictors of restrictive and obstructive airway pattern in a non-selected Malaysian population
title_full Defining the prevalence and predictors of restrictive and obstructive airway pattern in a non-selected Malaysian population
title_fullStr Defining the prevalence and predictors of restrictive and obstructive airway pattern in a non-selected Malaysian population
title_full_unstemmed Defining the prevalence and predictors of restrictive and obstructive airway pattern in a non-selected Malaysian population
title_short Defining the prevalence and predictors of restrictive and obstructive airway pattern in a non-selected Malaysian population
title_sort defining the prevalence and predictors of restrictive and obstructive airway pattern in a non-selected malaysian population
url http://journalarticle.ukm.my/16276/
http://journalarticle.ukm.my/16276/
http://journalarticle.ukm.my/16276/1/14_ms0422_pdf_21957.pdf