Development of nanoemulsion incorporated with Hibiscus sabdariffa for cosmeceutical application

Hibiscus sabdariffa (HS) has been reported to possess a crucial content of bioactive compounds, such as phenolic acids and flavonoids, therefore, HS was recognized as a source of antioxidants. Due to that, the development of nanoemulsion incorporated with HS appears promising for cosmeceutical app...

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Main Authors: Nur Royhaila Mohamad, Siti Salwa Abd Gani, Roswanira Abdul Wahab, Uswatun Hasanah Zaidan
Format: Article
Language:English
Published: Penerbit Universiti Kebangsaan Malaysia 2019
Online Access:http://journalarticle.ukm.my/14669/
http://journalarticle.ukm.my/14669/1/48_02_11.pdf
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author Nur Royhaila Mohamad,
Siti Salwa Abd Gani,
Roswanira Abdul Wahab,
Uswatun Hasanah Zaidan,
author_facet Nur Royhaila Mohamad,
Siti Salwa Abd Gani,
Roswanira Abdul Wahab,
Uswatun Hasanah Zaidan,
author_sort Nur Royhaila Mohamad,
building UKM Institutional Repository
collection Online Access
description Hibiscus sabdariffa (HS) has been reported to possess a crucial content of bioactive compounds, such as phenolic acids and flavonoids, therefore, HS was recognized as a source of antioxidants. Due to that, the development of nanoemulsion incorporated with HS appears promising for cosmeceutical application. This study is focused on the formulation of oil-inwater (O/W) nanoemulsions of HS to enhance the bioaccessibility of its active compounds. The influences of hydrophiliclipophilic balance (HLB) value of surfactant and grapeseed oil (GSO) to olive oil (OO) ratio on the droplet size, zeta potential, PDI and stability of the nanoemulsions were investigated. The results showed that the smallest particle size was obtained at 145.9 nm with PDI = 0.388 and zeta-potential = -41.1 mV in the systems prepared using HLB value of 12 and 2:1 ratio of GSO to OO. Then the selected nanoemulsion which based on the lowest particle size (NE-F6, GSO:OO = 2:1, and HLB = 12) showed good stability over time and temperature without no phase separation, creaming or cracking was spotted. The pH value of the NE-F6 was obtained at 5.2.
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spelling oai:generic.eprints.org:146692020-05-21T14:08:14Z http://journalarticle.ukm.my/14669/ Development of nanoemulsion incorporated with Hibiscus sabdariffa for cosmeceutical application Nur Royhaila Mohamad, Siti Salwa Abd Gani, Roswanira Abdul Wahab, Uswatun Hasanah Zaidan, Hibiscus sabdariffa (HS) has been reported to possess a crucial content of bioactive compounds, such as phenolic acids and flavonoids, therefore, HS was recognized as a source of antioxidants. Due to that, the development of nanoemulsion incorporated with HS appears promising for cosmeceutical application. This study is focused on the formulation of oil-inwater (O/W) nanoemulsions of HS to enhance the bioaccessibility of its active compounds. The influences of hydrophiliclipophilic balance (HLB) value of surfactant and grapeseed oil (GSO) to olive oil (OO) ratio on the droplet size, zeta potential, PDI and stability of the nanoemulsions were investigated. The results showed that the smallest particle size was obtained at 145.9 nm with PDI = 0.388 and zeta-potential = -41.1 mV in the systems prepared using HLB value of 12 and 2:1 ratio of GSO to OO. Then the selected nanoemulsion which based on the lowest particle size (NE-F6, GSO:OO = 2:1, and HLB = 12) showed good stability over time and temperature without no phase separation, creaming or cracking was spotted. The pH value of the NE-F6 was obtained at 5.2. Penerbit Universiti Kebangsaan Malaysia 2019-05 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/14669/1/48_02_11.pdf Nur Royhaila Mohamad, and Siti Salwa Abd Gani, and Roswanira Abdul Wahab, and Uswatun Hasanah Zaidan, (2019) Development of nanoemulsion incorporated with Hibiscus sabdariffa for cosmeceutical application. Malaysian Applied Biology, 48 (2). pp. 77-81. ISSN 0126-8643 http://www.mabjournal.com/index.php?option=com_content&view=article&id=921&catid=59:current-view&Itemid=56
spellingShingle Nur Royhaila Mohamad,
Siti Salwa Abd Gani,
Roswanira Abdul Wahab,
Uswatun Hasanah Zaidan,
Development of nanoemulsion incorporated with Hibiscus sabdariffa for cosmeceutical application
title Development of nanoemulsion incorporated with Hibiscus sabdariffa for cosmeceutical application
title_full Development of nanoemulsion incorporated with Hibiscus sabdariffa for cosmeceutical application
title_fullStr Development of nanoemulsion incorporated with Hibiscus sabdariffa for cosmeceutical application
title_full_unstemmed Development of nanoemulsion incorporated with Hibiscus sabdariffa for cosmeceutical application
title_short Development of nanoemulsion incorporated with Hibiscus sabdariffa for cosmeceutical application
title_sort development of nanoemulsion incorporated with hibiscus sabdariffa for cosmeceutical application
url http://journalarticle.ukm.my/14669/
http://journalarticle.ukm.my/14669/
http://journalarticle.ukm.my/14669/1/48_02_11.pdf