Molecular biology approaches to quantify subcellular localisation of mRNA therapeutics
Messenger RNA (mRNA) therapeutics hold promise for treating diverse diseases but face delivery challenges, as effective cytosolic entry and subsequent translation are limited by endosomal entrapment. Nanoparticles aid mRNA transport across cell membranes, yet only a fraction of mRNA escapes endosome...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2025
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| Online Access: | https://eprints.nottingham.ac.uk/81355/ |