Reconstitution of the Core Ccr4-Not Complex and Evidence for Possible Interaction between YTHDF2 and Human CNOT9

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Reconstitution of the Core Ccr4-Not Complex and Evidence for Possible Interaction between YTHDF2 and Human CNOT9

In eukaryotic cells, shortening and removal of the poly(A) tail of cytoplasmic mRNA (deadenylation) is a key step in mRNA degradation. Studies have shown that the Ccr4-Not complex plays a fundamental role in regulating gene expression at the posttranscriptional level. The different parts of this com...

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Bibliographic Details
Main Author:	Gong, Yutong
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2025
Subjects:	Ccr-4-NOT complex gene expression proteins deadenylation of mRNA
Online Access:	https://eprints.nottingham.ac.uk/81322/

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