Reconstitution of the Core Ccr4-Not Complex and Evidence for Possible Interaction between YTHDF2 and Human CNOT9

In eukaryotic cells, shortening and removal of the poly(A) tail of cytoplasmic mRNA (deadenylation) is a key step in mRNA degradation. Studies have shown that the Ccr4-Not complex plays a fundamental role in regulating gene expression at the posttranscriptional level. The different parts of this com...

Full description

Bibliographic Details
Main Author: Gong, Yutong
Format: Thesis (University of Nottingham only)
Language:English
Published: 2025
Subjects:
Online Access:https://eprints.nottingham.ac.uk/81322/