Investigating ApoE4-Mediated Molecular Alterations in H4 Neuroglioma Cells of Alzheimer’s Disease Using OrbiSIMS and LC-MS/MS.

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Investigating ApoE4-Mediated Molecular Alterations in H4 Neuroglioma Cells of Alzheimer’s Disease Using OrbiSIMS and LC-MS/MS.

Apolipoprotein E4 (ApoE4) is the significant risk gene for late-onset Alzheimer’s disease (AD), which is not only associated with the AD pathological features, including amyloid-β deposition, phosphorylation of Tau proteins and neuroinflammation; but also involved with metabolism, neuron growth, and...

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Bibliographic Details
Main Author:	Lu, Li
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2025
Subjects:	OrbiSIMS Metabolomics Lipidomics Alzheimer's disease Apolipoproteins
Online Access:	https://eprints.nottingham.ac.uk/81294/

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