Investigating ApoE4-Mediated Molecular Alterations in H4 Neuroglioma Cells of Alzheimer’s Disease Using OrbiSIMS and LC-MS/MS.
Apolipoprotein E4 (ApoE4) is the significant risk gene for late-onset Alzheimer’s disease (AD), which is not only associated with the AD pathological features, including amyloid-β deposition, phosphorylation of Tau proteins and neuroinflammation; but also involved with metabolism, neuron growth, and...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2025
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| Online Access: | https://eprints.nottingham.ac.uk/81294/ |