The impacts of endothelial cell senescence on ageing-related blood-brain barrier dysfunction and the potential therapeutic strategies

Background: Disruption of the blood-brain barrier (BBB) contributes to various agerelated neurological disorders. Brain microvascular endothelial cells (BMECs) are the most critical components of the BBB, forming a tightly sealed yet selectively permeable monolayer to maintain central nervous system...

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Bibliographic Details
Main Author: Ya, Jingyuan
Format: Thesis (University of Nottingham only)
Language:English
Published: 2025
Subjects:
Online Access:https://eprints.nottingham.ac.uk/80866/