The effect of ageing on the blood-brain barrier: The potential of nanoparticle drug delivery systems to target cerebrovascular changes

Within physiological ageing, recent evidence has shown that alterations to blood-brain barrier (BBB) permeability are potentially caused by a shift towards non-selective entry of systemic molecules into the brain via transcytosis. The ability to exploit this to deliver therapeutic molecules to targe...

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Bibliographic Details
Main Author: Bates, Jessica
Format: Thesis (University of Nottingham only)
Language:English
Published: 2025
Subjects:
Online Access:https://eprints.nottingham.ac.uk/80442/