Design, Synthesis, and Development of Novel Intracellular Allosteric Modulators of CXC Chemokine Receptor 1 and 2
Chemokine receptors, CXC chemokine receptor 1 (CXCR1) and CXC chemokine receptor 2 (CXCR2) play pivotal roles in various neutrophil-mediated inflammatory diseases, including COPD, asthma, and psoriasis. Additionally, evidence is mounting for the involvement of neutrophils and the CXCL8-CXCR1/2 axis...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2024
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| Online Access: | https://eprints.nottingham.ac.uk/79820/ |