Structural studies of Von Willebrand Factor regulators for Thrombotic Thrombocytopenic Purpura.
Blood clotting requires an urgent and efficient response with von Willebrand factor (VWF) playing a major role through recruitment of platelets forming a haemostatic plug. VWF is a large multi-domain glycoprotein, with the A1 domain for platelet binding via Gp1bα and the A2 domain containing the cle...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2024
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| Online Access: | https://eprints.nottingham.ac.uk/79450/ |