α-Amidobenzylboronates and β-Ketobenzylboronates as Inhibitors of Plasma Kallikrein

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α-Amidobenzylboronates and β-Ketobenzylboronates as Inhibitors of Plasma Kallikrein

Hereditary angioedema (HAE), a rare genetic disorder, is associated with uncontrolled plasma kallikrein (PKa) enzyme activity leading to often severe bradykinin-induced swelling in subcutaneous and submucosal membranes in various locations of the body. This thesis describes a series of α-amidoben...

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Bibliographic Details
Main Author:	Allison, Matthew
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2024
Subjects:	Plasma Kallikrein Inhibitor Covalent Hereditary Angioedema
Online Access:	https://eprints.nottingham.ac.uk/78452/

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