α-Amidobenzylboronates and β-Ketobenzylboronates as Inhibitors of Plasma Kallikrein
Hereditary angioedema (HAE), a rare genetic disorder, is associated with uncontrolled plasma kallikrein (PKa) enzyme activity leading to often severe bradykinin-induced swelling in subcutaneous and submucosal membranes in various locations of the body. This thesis describes a series of α-amidoben...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2024
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| Online Access: | https://eprints.nottingham.ac.uk/78452/ |