From the extracellular matrix to the microprocessor: Investigating the post-transcriptional regulation of miRNA-155 by tenascin-C

A highly controlled type of short RNA sequences called microRNAs (miRNAs) regulates cellular processes via translational repression or degradation of target mRNAs. In particular, miRNA-155 plays a central role in the macrophage inflammatory response to infection, with dysregulation of miR-155 associ...

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Bibliographic Details
Main Author: Dawson, Owen
Format: Thesis (University of Nottingham only)
Language:English
Published: 2024
Subjects:
Online Access:https://eprints.nottingham.ac.uk/78422/