An integrated approach to understanding the architecture of DDX3-mediated HIV translation pre-initiation complex
HIV transcripts contain highly structured 5′ untranslated regions (5′ UTR), necessitating a non-canonical translation pre-initiation complex (PIC), to allow ribosomes to bind and carry out translation. The PIC uniquely comprises the human DEAD-box RNA helicase, DDX3, bound directly to the trans-acti...
| Main Author: | |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2024
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/78378/ |