Investigating the Mechanism of Action of Antitumour Benzoprims

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Investigating the Mechanism of Action of Antitumour Benzoprims

KRAS is one of the most frequently mutated oncogenes, with activating mutations occurring in ~ 20% of all human cancers, including >90% of pancreatic cancer, ~40% of colorectal cancer (CRC) and ~30% of non-small cell lung cancer (NSCLC). Until recently, KRAS inhibitors have not been successful cl...

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Bibliographic Details
Main Author:	Hatfield, Amelia
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2024
Subjects:	oncogenes benzoprims cell inhibitors cancer cells
Online Access:	https://eprints.nottingham.ac.uk/78346/

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