Investigating the Mechanism of Action of Antitumour Benzoprims

KRAS is one of the most frequently mutated oncogenes, with activating mutations occurring in ~ 20% of all human cancers, including >90% of pancreatic cancer, ~40% of colorectal cancer (CRC) and ~30% of non-small cell lung cancer (NSCLC). Until recently, KRAS inhibitors have not been successful cl...

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Bibliographic Details
Main Author: Hatfield, Amelia
Format: Thesis (University of Nottingham only)
Language:English
Published: 2024
Subjects:
Online Access:https://eprints.nottingham.ac.uk/78346/