Control of collateral formation as a therapeutic for cardiovascular disease
Peripheral arterial disease (PAD) leads to tissue ischaemia due to vascular insufficiency. In response to this ischaemia, circulating monocytes produce vascular endothelial growth factor (VEGF-A), a crucial regulator of angiogenesis. Monocytes exhibit increased overexpression of the anti-angiogenic...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2024
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| Online Access: | https://eprints.nottingham.ac.uk/78268/ |