Photocatalytic Tryptophan Alkylation for Chemoselective Peptide Modification

A chemoselective peptide functionalisation strategy via photocatalytic tryptophan (Trp) modification has been developed. The versatility of the reaction is demonstrated by tethering a variety of difluoroalkyl groups to Trp using an organic photocatalyst and short irradiation times with visible light...

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Bibliographic Details
Main Author: Lee, Joanna
Format: Thesis (University of Nottingham only)
Language:English
Published: 2024
Subjects:
Online Access:https://eprints.nottingham.ac.uk/78245/