Exploring the role of multidrug exporters and extracellular vesicles in medulloblastoma chemoresistance

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Exploring the role of multidrug exporters and extracellular vesicles in medulloblastoma chemoresistance

Introduction: Medulloblastoma is the most common malignant paediatric brain tumour; patients harbouring relapsed and metastatic tumours exhibit a dismal 5-year survival prognosis, where less than 10% of patients respond to current treatments. Whilst there have been considerable steps forward in our...

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Bibliographic Details
Main Author:	Wade, Philippa
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2024
Subjects:	Medulloblastoma; Drug resistance mechanisms; Brain Tumours; ABCB1; ABCC1; ABCG2; Metabolic pathways
Online Access:	https://eprints.nottingham.ac.uk/78238/

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