Developing a chemically defined, xeno-free platform to differentiate human induced pluripotent stem cells to type 2 alveolar epithelial cells of the lung

Type 2 alveolar epithelial cells (AECs) are the facultative progenitors of the lung alveolar epithelium, as they self-renew and dedifferentiate into type 1 AECs under homeostatic conditions and in response to chronic injury. They are responsible for the synthesis and secretion of a lipoprotein rich...

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Bibliographic Details
Main Author: Reed, Liam
Format: Thesis (University of Nottingham only)
Language:English
English
English
Published: 2024
Subjects:
Online Access:https://eprints.nottingham.ac.uk/77961/