Mitigating the harm caused by Pseudomonas aeruginosa in Cystic Fibrosis

Cystic fibrosis (CF) affects up to 100,000 people worldwide. Defects in the Cystic Fibrosis Transmembrane Regulator (CFTR) gene cause abnormally viscid secretions at epithelial surfaces. In the lungs the abnormal secretions reduce clearance of both pathogens and sputum, predisposing to recurrent lun...

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Bibliographic Details
Main Author: Palser, Sally C.
Format: Thesis (University of Nottingham only)
Language:English
Published: 2024
Subjects:
Online Access:https://eprints.nottingham.ac.uk/77908/