Universal sensors for identifying use-dependent intracellular allosteric modulators of G protein coupled receptors
G protein-coupled receptors (GPCRs) represent the largest family of cell surface receptors targeted by therapeutics. Their diverse signalling capabilities lead to involvement in a wide range of physiological and disease responses. The vast majority of molecules currently available to target GPCRs ar...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2024
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| Online Access: | https://eprints.nottingham.ac.uk/77576/ |