Investigating the roles of Gfi1/1b transcription factors, Lsd1 histone demethylase and long non coding RNA 1/2 genes in haematopoiesis during zebrafish embryogenesis

Cellular differentiation entails the activation of mature cell markers and the repression of genes that are characteristic for immature cell states and alternative differentiation paths. Their repression involves transcriptional repressors and numerous non-coding RNAs that act to suppress gene...

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Bibliographic Details
Main Author: Khalaf, Samer Naji
Format: Thesis (University of Nottingham only)
Language:English
Published: 2024
Subjects:
Online Access:https://eprints.nottingham.ac.uk/77312/