Investigations into β2-adrenoceptor pharmacology: kinetic analysis, mechanotransduction and allosteric modulation
The β2-adrenoceptor (β2AR) is a prototypical class A member of the G protein-coupled receptor (GPCR) superfamily of membrane-bound receptors. Activation of the β2AR is associated primarily with the relaxation of airway and vascular smooth muscle and has been targeted extensively by β-agonists to tre...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2024
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| Online Access: | https://eprints.nottingham.ac.uk/77100/ |