A link between NMDA receptor hypofunction and GABAergic inhibition in the modulation of cognition: a comparison of neural and cognitive changes in rat models of NMDA receptor hypofunction and of prefrontal and hippocampal neural disinhibition
NMDA receptor (NMDAR) hypofunction and impaired GABAergic inhibition, so-called neural disinhibition, in the hippocampus and prefrontal cortex, have both been implicated in the pathophysiology of schizophrenia. Moreover, it has been suggested that NMDAR hypofunction and neural disinhibition are mech...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2024
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| Online Access: | https://eprints.nottingham.ac.uk/77029/ |