In vitro modelling of respiratory infections in idiopathic pulmonary fibrosis (IPF) using human induced pluripotent stem cell (hiPSCs)-derived alveolar epithelial type II cells

Idiopathic pulmonary fibrosis (IPF) is a chronic, interstitial lung disease estimated to affect 4.5 individuals per 10,000[1]. It is characterised by the accumulation of extracellular matrix in the lung interstitium, which disrupts the normal architecture and impairs lung function resulting in sever...

Full description

Bibliographic Details
Main Author: Serna Valverde, Ana Lilia
Format: Thesis (University of Nottingham only)
Language:English
Published: 2023
Subjects:
Online Access:https://eprints.nottingham.ac.uk/76715/