Application of autoantibody binding curve characteristics and machine learning methods for improving the diagnostic performance of an early detection test for lung cancer

The EarlyCDT®-Lung test has been technically and clinically validated for the early detection of lung cancer with a sensitivity ~40% and a specificity of ~90% through measurement of a panel of seven serum autoantibodies. The test generates curves of autoantibody binding to a titrated series of capt...

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Bibliographic Details
Main Author: Allen, Jared
Format: Thesis (University of Nottingham only)
Language:English
Published: 2023
Subjects:
Online Access:https://eprints.nottingham.ac.uk/76628/