Unphosphorylated dimers are not required for the assembly of active STAT1 and STAT3 homo-and heterodimers
STATs are latent signalling proteins and transcription factors that are activated by phosphorylation upon ligand binding to cytokine receptors. All seven mammalian STATs form dimers upon activation. So far, research focused on homodimers, but it is now recognised that some STATs can also form hetero...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2023
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| Online Access: | https://eprints.nottingham.ac.uk/76007/ |