Design, Synthesis, and Development of Novel Fluorescently Labelled Allosteric Probes for the Human Beta2-Adrenoceptor

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Design, Synthesis, and Development of Novel Fluorescently Labelled Allosteric Probes for the Human Beta2-Adrenoceptor

It has started to be questioned that the success rate of traditional G protein-coupled receptor (GPCR)-based drug discovery is in decline related to the difficulty in selectively targeting the orthosteric binding site at receptors that display high sequence homology between subtypes. In the last dec...

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Bibliographic Details
Main Author:	Tuzer, Cemre
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2023
Subjects:	G protein-coupled receptors GPCR allosteric proteins
Online Access:	https://eprints.nottingham.ac.uk/74480/

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