Design, Synthesis, and Development of Novel Fluorescently Labelled Allosteric Probes for the Human Beta2-Adrenoceptor
It has started to be questioned that the success rate of traditional G protein-coupled receptor (GPCR)-based drug discovery is in decline related to the difficulty in selectively targeting the orthosteric binding site at receptors that display high sequence homology between subtypes. In the last dec...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2023
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| Online Access: | https://eprints.nottingham.ac.uk/74480/ |