Effects of khat ethanol extract, cathinone and cathine on cytochrome P450 activities in vitro, molecular docking CYP-cathinone and CYP-cathine interactions and in vivo effects on Caenorhabditis elegans

Khat (Catha edulis Forsk), a natural amphetamine-like psychostimulant plant, and its major active compounds cathinone and cathine are consumed by many not only for cultural practice but also for its appetite suppressing effects and often co-abused with alcohols and polydrugs. Concurrent intake of he...

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Bibliographic Details
Main Author: Lim, Sharoen Yu Ming
Format: Thesis (University of Nottingham only)
Language:English
Published: 2024
Subjects:
Online Access:https://eprints.nottingham.ac.uk/74441/