Investigating the role of eIF4A2 in the spatial regulation of metabolic adaptation to hypoxia in colorectal cancer
Colorectal cancer is the third most common cancer worldwide and ranks second for cancer-related mortality. Hypoxia (< 1% pO2) is found in up to 50% of colorectal tumours and is associated with poor patient prognosis, increased metastatic potential and resistance to therapy. Hypoxia stabilises the...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2023
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| Online Access: | https://eprints.nottingham.ac.uk/73892/ |