STRUCTURAL AND BIOPHYSICAL ANALYSIS OF UBE3A AND PARTNER PROTEIN COMPLEXES

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STRUCTURAL AND BIOPHYSICAL ANALYSIS OF UBE3A AND PARTNER PROTEIN COMPLEXES

UBE3A is a human E3 ubiquitin ligase, responsible for the transfer of ubiquitin onto substrates to target them for degradation and other cellular processes. UBE3A has been implicated in a range of neurodevelopmental disorders, most notably Angelman Syndrome, but also Dup15Q syndrome, autism spectrum...

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Bibliographic Details
Main Author:	Cowan, Emma
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2023
Subjects:	UBE3A ubiquitin ligase onocogenes enzymes
Online Access:	https://eprints.nottingham.ac.uk/73465/

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