STRUCTURAL AND BIOPHYSICAL ANALYSIS OF UBE3A AND PARTNER PROTEIN COMPLEXES
UBE3A is a human E3 ubiquitin ligase, responsible for the transfer of ubiquitin onto substrates to target them for degradation and other cellular processes. UBE3A has been implicated in a range of neurodevelopmental disorders, most notably Angelman Syndrome, but also Dup15Q syndrome, autism spectrum...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2023
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| Online Access: | https://eprints.nottingham.ac.uk/73465/ |