Rab-SPIRE interaction: the molecular mechanism of the interaction between Rab27a and SPIRE1

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Rab-SPIRE interaction: the molecular mechanism of the interaction between Rab27a and SPIRE1

Rab27a is a small GTPase that regulates organelle transport and exocytosis by recruiting effector proteins to membranes. SPIRE1/2 are membrane associated actin nucleators recently identified as Rab27a effectors. In melanocytes they interact with Rab27a via their C-terminal domains (SFH) and assemble...

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Bibliographic Details
Main Author:	Alghamdi, Asmahan
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2023
Subjects:	Small GTPase Guanosine triphosphatase Rab27a SPIREs SPIRE1 AlphaFold
Online Access:	https://eprints.nottingham.ac.uk/73066/

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