Rab-SPIRE interaction: the molecular mechanism of the interaction between Rab27a and SPIRE1
Rab27a is a small GTPase that regulates organelle transport and exocytosis by recruiting effector proteins to membranes. SPIRE1/2 are membrane associated actin nucleators recently identified as Rab27a effectors. In melanocytes they interact with Rab27a via their C-terminal domains (SFH) and assemble...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2023
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| Online Access: | https://eprints.nottingham.ac.uk/73066/ |